PlexusDx Reviews 

90
•
TrustScore 4.5 out of 5

4.4

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Review summary

Created with AI, based on recent reviews

Considering 86 reviews, reviewers overwhelmingly had a great experience with this company. Customers frequently praise the fast shipping, seamless delivery, and the incredibly streamlined process for getting started with their medical prescriptions. People consistently note that the support team, care members, and medical staff provide prompt, helpful guidance and clear communication throughout the entire health journey. However, some reviewers were not happy with occasional order errors, delivery delays, or prescription mistakes that required extra time and effort to resolve. A few other people also felt that the initial dosage increases were too slow or experienced frustrating communication gaps with the clinical support team.

What people talk about most

Product

Customers had positive experiences with product, reporting significant weight loss, a noticeable decrease in... See more

Customer service

Reviewers mention positive feedback about customer service, highlighting that support agents and care teams... See more

User experience

Users describe positive interactions with user experience, highlighting how easy it is to navigate the... See more

Service

Clients share positive opinions on service, highlighting quick communication, fast response times, and... See more

Delivery service

Consumers find delivery service to be positive, highlighting extremely quick shipping and reliable... See more

Reviews shaping this summary

Rated 4 out of 5 stars

I am a little frustrated that my prescription was made out to stay on the same dose for 12 weeks so that is why I gave 4 stars. I am really happy with my meeting with a doctor who is hoping to help me... See more

Company replied

Rated 5 out of 5 stars

The team has been so helpful and responsive! I had a great meeting with the medical director, all of my questions were answered. PlexusRX has made me feel supported and excited along this journey! Dow... See more

Company replied

Rated 5 out of 5 stars

My experience with PlexusDx has been really fantastic. Questions answered within minutes and first dose arrived next day. They are really on top of things and J would highly recommend them. I did loo... See more

Company replied

Rated 5 out of 5 stars

What started off a little bit rocky turned into a phenomenal experience. I had placed an order right before a major US holiday causing a shipping Delay. The COO, Adam, MADE SURE to make it right. He p... See more

Company replied


Company details

  1. Fitness and nutrition
  2. also in
  3. Vitamin & Supplements Shop
  4. Wellness Programme

Written by the company

PlexusDx is a science-driven health testing company that empowers individuals to make more informed, personalized health decisions using at-home genetic testing and blood tests. PlexusDx combines DNA analysis and lab-based blood biomarkers to deliver actionable insights across nutrition, metabolism, methylation, hormones, cardiovascular health, inflammation, longevity, and overall wellness. All tests are easy to complete from home and processed by certified laboratories, with results delivered through a secure digital health portal. A core differentiator of PlexusDx is its ability to use a customer’s genetic and blood test results to personalize diet and meal plan recommendations. Rather than generic nutrition advice, PlexusDx analyzes key genetic pathways and blood markers to help guide food choices, dietary patterns, and lifestyle strategies aligned with an individual’s unique biology. PlexusDx also leverages genetic and blood data to provide personalized supplement recommendations, helping customers better understand which nutrients may support their health goals based on their results. These recommendations are designed to complement diet and lifestyle decisions—not replace medical care—and are presented in a clear, easy-to-understand format. PlexusDx is especially known for its advanced Genetic Methylation Test and Methylation Blood Tests, which focus on critical biochemical pathways involved in energy production, detoxification, nutrient metabolism, and cellular function. By pairing genetic methylation insights with blood-based validation, PlexusDx offers a deeper, more complete view of methylation-related health factors. Results are delivered through the PlexusDx Results Portal, where customers can view their reports, personalized insights, and recommendations in one centralized, secure platform. PlexusDx supports HSA and FSA payments and is committed to transparency, data accuracy, and exceptional customer support. Whether you’re seeking personalized nutrition guidance, deeper insight into methylation pathways, or proactive wellness testing, PlexusDx provides trusted, data-driven tools designed to support informed health and lifestyle decisions.


Contact info

4.4

Excellent

TrustScore 4.5 out of 5

90 reviews

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Replied to 100% of negative reviews

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4.4

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(90)

90 reviews in the last 12 months

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Rated 1 out of 5 stars

Avoid PlexusDx – Terrible Customer Service and Nightmare Refund Process

Do not waste your time or money with PlexusDx. My experience with them has been an absolute nightmare regarding both starting a simple prescription and trying to get my money back.

I signed up for their tirzepatide intake and prescription services, but I quickly lost all confidence in their clinical care model. The process was plagued by repeated intake errors, frustratingly redundant communication loops, and a total lack of clear answers from their clinical team.

When I gave up and requested an immediate cancellation and full refund, the hassle only got worse. Despite being told by multiple representatives that my cancellation request was submitted to billing, getting straight answers or direct contact information for their billing department has felt impossible. As of today, I have not received a refund.

Save yourself the headache and go with a provider that actually has competent clinical support and transparent billing. Getting a prescription started shouldn't be this complicated, and getting your money back shouldn’t be a fight.

19 August 2026
Unprompted review
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Reply from PlexusDx

Hi Vicki, I’m reaching out personally after reviewing your experience with PlexusDx, including the full history of your case.

You were right to be frustrated. I reviewed the timeline closely, and the part that concerns me most is that your provider approved your prescription on August 17 at 8:01 PM ET, and your order was moved into the pharmacy order processing queue later that evening at 10:55 PM.

Unfortunately, the following morning, the order was pulled back out of the pharmacy queue because of a clarification question from your provider.

After reviewing the case, that additional step should not have delayed your order.

Your provider had already reviewed the information available and your script was consistent with what you had been asking for.

In other words, you had done what was asked of you, your prescription had been approved, and we created additional confusion that unnecessarily stopped the process.

I’m sorry and that is not the experience we want anyone to have with PlexusDx.

I can confirm that your full refund is now processing. Depending on your bank or credit card company, it may take a few business days before the credit appears back in your account.

I also saw something in your messages that stood out to me: before everything went sideways, you were genuinely excited to try your selected treatment. So I’d like to offer you something with no strings attached.

We are still completing your full refund regardless, but if you are open to giving us one opportunity to make this right, please make sure to check the email I sent.

There would be no obligation to continue afterward. We don't operate on a subscription basis and if you choose to not refill with us then there will never be another charge from us.

You should not have to pay for our operational mistake, and I’d rather earn back some of your confidence by actually delivering what we originally promised.

If you’d like us to proceed with our offer, just reply and let me know. If you’d prefer to move on, I completely understand, and your refund will continue processing either way.

Thank you for taking the time to explain what happened. Your feedback exposed a real breakdown in our process that we need to fix.

-Jay Hastings, CEO

Rated 5 out of 5 stars

What started off a little bit rocky…

What started off a little bit rocky turned into a phenomenal experience. I had placed an order right before a major US holiday causing a shipping Delay. The COO, Adam, MADE SURE to make it right. He provided top notch customer service and communicated every update with me. He reached out personally to apologize and put my anxiety at ease. He is professional, helpful, and provided the best customer service I have ever received. 5 outta 5 stars. Ill be sticking with PlexusDx for my prescription needs.

2 July 2026
Unprompted review
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Reply from PlexusDx

Thank you for the kind words Gina! Not only did I share this with the entire team (it’s a team effort), I’ll have to print this one up and put in on the family refrigerator. 😅 - Adam Valentine, COO

Rated 5 out of 5 stars

So far my experience has been… extremely wonderful

So far my experience has been wonderful. I got approved fast. And I signed up on a Sunday night my shipment got to me fast. I was able to up my dosage after a month and I'm seeing better results than I do on Ozepic. I've only experienced a little of nausea and throwing up but after my second month I'm feeling much better. Dr responds fast and the price is affordable will definitely recommend.

10 July 2026
Unprompted review
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Reply from PlexusDx

Heather, this made our day and I am happy to see the nausea has passed. I post every review internally so we can learn from our customers (kind of like how I put my kid's drawings on the refrigerator). - Adam Valentine, COO.

Rated 5 out of 5 stars

Fast service

Fast service, easy process and great communication and customer service.

14 August 2026
Unprompted review
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Reply from PlexusDx

Thank you Ashley! We started this company to help people and it is always great to hear we are doing that. We want to make things easy so you can concentrate on your health. -Adam, COO

Rated 5 out of 5 stars

Easy to initiated with great follow up

Easy to initiated with great follow up. Best price for what I need. I’m a retired nurse and I appreciate the review of my progress from their staff.

14 August 2026
Unprompted review
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Reply from PlexusDx

Thank you Holly! I made sure everyone here knows about your review. What a great way to start the weekend! -Adam, COO

Rated 5 out of 5 stars

Very happy with all the questions they…

Very happy with all the questions they answered and how responsive they were. They ship super quick and are very affordable. I feel great and have been seeing positive results. Impressed.

12 August 2026
Unprompted review
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Reply from PlexusDx

Abby, this was the best way to start our Friday. I shared your review to the rest of the team. All reviews are a team effort over here. Reach out to us whenever you can to tell us how we can make your experience better. - Adam, COO

Rated 5 out of 5 stars

Great product and excellent…

Great product and excellent communication

12 August 2026
Unprompted review
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Reply from PlexusDx

Cristy! Thank you for the review. Always let us know how we can improve your experience. Our biggest changes have come from our customers. - Adam, COO

Rated 5 out of 5 stars

Simplicity of explaining the process…

Simplicity of explaining the process and what it entails. Quick response to questions asked. The price is manageable and delivery is quick. Questions and visit are brief and the ability to start and stop your program is also benificial.

30 June 2026
Unprompted review
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Reply from PlexusDx

Wes, thank you for the review! I shared your experience with the team. Sorry for the late reply. We read every single review so we always improve. -Adam, COO

Rated 5 out of 5 stars

Great job

Great job, thanks for all the great info

11 August 2026
Unprompted review
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Reply from PlexusDx

Thank you Davide! A five star review is a great way to start our Friday. -Adam, COO

Rated 5 out of 5 stars

Excellent

So far the service has been quick and exceptional. I can contact real people and they were very helpful when I needed time to make a payment. The medication is perfect and I can’t think of one bad thing to say. Outstanding.

9 August 2026
Unprompted review
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Reply from PlexusDx

C. C, I sent your review to the entire team. We take our customer service personally and you made our Sunday - Adam Valentine, COO

Rated 5 out of 5 stars

The service team is great

The service team is great and very responsive. They actively assisted me getting the shipment sent after a brief delay at the pharmacy and the refill process was seamless!

24 June 2026
Unprompted review
Rated 1 out of 5 stars

Orders Unfulfilled, with no ability to provide a timeline

I placed an initial order for 3 products MIC-B12, sermorelin and GLP-squared pill. The products were approved, then I realized they made an error. I paid for the GLP-squared pill and they tried to ship me the injection. They shipped me the MIC-b12 injection I ordered and nothing else. I have followed up 7 times to see where the status of my order is, I have also requested to cancel due to lack of understanding their own supply chain and knowing where my order is and a timeline of when it will ship. This has been going on for over almost 3 weeks now.

9 July 2026
Unprompted review
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Reply from PlexusDx

Good morning Christina, this is Adam Valentine, COO of PlexusDx (I just sent you a text from my personal number).

1. I want to personally apologize for the pharmacy that caused this horrendous service. We have since severed ties with them from our network. Yourself and others were impact and we were not told of the backup. No excuses, they are gone.

2. I I have escalated a full refund to billing. Keep whatever medication comes your way. You’re not on a subscription service.

I look forward to speaking with you personally about your experience. I am sorry we failed you.

Rated 1 out of 5 stars

Poor customer Service

I was really hopeful with this as the price was affordable but upon getting signed up quickly with Adam I have been reaching out with questions since the 16th, it is now the 21st, with no response from my team. I am ready to cancel my subscription because I feel like I want a team who cares and is always checking in

16 July 2026
Unprompted review
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Reply from PlexusDx

Good morning Lilliana, this is Adam Valentine, COO of PlexusDx. I just sent you a text from my personal cell.

1. I want to personally apologize for the pharmacy that caused this horrendous service. We have since severed ties with them from our network. Yourself and others were impacted and we were not told of the backup in orders.

2. You will have a full refund. Keep whatever medication comes your way. You’re not on a subscription service.

If you have time I will make myself available to speak with you today.

Rated 5 out of 5 stars

Genetic test and one hour consult

I did the genetic testing (which was easy to do) and one hour consult with Jayden Lee EMBA, Pharm D. I really appreciated the results and time taken. He did help me not panic at all the yellow/red on my test results. 😅

17 July 2026
Unprompted review
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Reply from PlexusDx

Thank you Tori! Yes, I am a little late to responding, but I can assure you we read every single review. Jayden was made aware of your review the moment you posted it. We created this company to help people (and not make them panic)!

Rated 5 out of 5 stars

I don't usually write reviews

I don't usually write reviews, but this one was worth it.

I've done plenty of blood work over the years, and while it tells you what's happening right now, I always felt like I was missing the "why." The PlexusDX DNA test filled in a lot of those gaps. It gave me insights into how my body is wired, everything from metabolism and inflammation to nutrient needs, stress response, recovery, and hormone pathways.

What I appreciated most was that it didn't feel like one of those gimmicky DNA reports that tells you whether you like cilantro. The information was detailed, practical, and actually useful. It helped explain why certain diets, supplements, and exercise programs have worked for me, while others never seemed to make a difference.

One thing that really stood out was the peptide pathway information. I haven't seen that included in other DNA tests I've looked at. I ordered the peptides and the supplemnets they suggested. I can't wait!

The report was easy to navigate, professionally put together, and gave me a much better understanding of my health than I expected. Since your DNA doesn't change, it's something I'll be able to reference for years instead of repeating expensive tests over and over.

If you're someone who wants a more personalized approach to your health instead of guessing, I'd absolutely recommend it.

16 July 2026
Unprompted review
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Reply from PlexusDx

Diana, I am a little late in responding but I can assure you the team saw your review the moment it posted. Your review is extremely thoughtful and it was circulated to the team shortly after posting. Just imagine us printing your review and attaching to our refrigerator at home. Our kids have refrigerator School Art, we have Customer Reviews :) -Adam, COO

Rated 5 out of 5 stars

Great customer service

So far, so good. Had a snag with logging in but finally got it resolved. Customer Service was superb! Adam was extremely helpful.

17 July 2026
Unprompted review
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Reply from PlexusDx

Thank you Lucinda! Always happy to help.

Rated 5 out of 5 stars

With the methylation test I would give…

With the methylation test I would give 5 stars. I purchased a consultation with Jaylin and it inspired me to look closer into supplements.
HOWEVER I purchase peptides, was approved, prescribed and billed. They HAVE NOT answered me on the portal. Instead they have sent me a message to complete an intake form.
DO THEY NOT KNOW WHAT THEY ARE DOING? I will call tomorrow. Depending on the response I may cancel peptides with them.

10 June 2026
Unprompted review
PlexusDx logo

Reply from PlexusDx

Good morning Brenda, this is Adam Valentine, COO of PlexusDx. I will text and call you personally with an update this morning. This is unacceptable service from a pharmacy within our network.

Rated 5 out of 5 stars

Important to Read

I wanted to take a moment to share my experience with PlexusDx, as I believe their level of care and professionalism truly stands out. From the very beginning, their team has been attentive, responsive, and eager to help, making the entire process seamless and reassuring. Every question I had even as a new customer navigating some unfamiliar territory was met with patience and thorough explanations, ensuring I understood each step and felt confident about my treatment.

What impressed me most was the genuine commitment to making sure I received exactly what I needed, whether it was clarifying medication details, assisting with logistics, or guiding me through the portal and intake process. The support team and clinical advisors were always accessible and proactive in their communication, which made a big difference in my overall experience.

If you’re looking for a company that puts customers first and goes above and beyond to deliver quality service, I highly recommend PlexusDx. Their expertise and dedication are matched only by their kindness and willingness to help. I will continue to spread the word, they are a true asset to anyone seeking precision wellness solutions.

Best regards,
John Infantolino

29 June 2026
Unprompted review

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