Samphire Neuroscience Reviews 99

TrustScore 4.5 out of 5

4.7

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Review summary

Created with AI, based on recent reviews

Looking at 54 reviews, reviewers overwhelmingly had a great experience with this company. Many customers describe the product as a life-changing game-changer, significantly improving their mood, reducing pain symptoms, and providing more control over their conditions. People appreciate the product's effectiveness in managing PMDD and PMS symptoms, often leading to a decrease in physical and mental discomfort, and even reducing the need for painkillers. The customer service and the team behind the product are consistently praised for being amazing, caring, responsive, and incredibly helpful, going above and beyond to support users. However, some customers experienced technical issues with the device, such as problems with charging or connectivity, requiring them to send it back for replacement. A few people also noted confusion regarding the tracking metrics and the lack of actionable insights from the collected data, questioning its meaningfulness.

What people talk about most

Product

Users describe positive interactions with the product, with many finding it to be life-changing for managing... See more

User experience

Reviewers mention positive feedback about user experience, with many finding the device easy to use and... See more

Customer service

Clients share positive opinions on customer service, consistently describing it as responsive, helpful, and... See more

Staff

Customers had positive experiences with staff, consistently praising their responsiveness, helpfulness, and... See more

Quality

Reviewers highlight positive aspects of quality, noting significant improvements in energy, mood, and a... See more

Reviews shaping this summary

Rated 5 out of 5 stars

Using a Nettle has changed my life. The week before my period, are now doable. Before Nettle, I felt overwhelmed, anxious and even angry the week before my period. Now that's replaced with a b... See more

Company replied

Rated 5 out of 5 stars

The Nettle has been life changing as someone with pcos and pmdd, and long term depression. It’s helped me to manage my mood and reduced my pain symptoms. It’s not like any other treatment I have exper... See more

Company replied

Rated 5 out of 5 stars

I’ve been using Nettle since it launched and it’s made such a noticeable difference in my pms and pmdd symptoms. I used to have at least 2-3 days every month where I couldn’t function, either due to c... See more

Company replied

Rated 5 out of 5 stars

Less crying, less snapping, just in general a more calm time before my periods. Between loosing weight and pre-menopause, my cycle has become notable longer than it used to be, and I'm so grateful tha... See more

Company replied


Company details

  1. #1 of 7 best companies in Medical technology manufacturer

Written by the company

Samphire Neuroscience is a neurotechnology company dedicated to maximizing the wellbeing of women by delivering pioneering neurotechnology and evidence-based solutions that are drug and hormone-free. Our products include Nettle™, a medically-approved brain stimulation device to tackle PMS and menstrual pain non-invasively, Lutea™, a wellness brain stimulation device to support women during hormonally challenging moments, and the Samphire App, which helps women understand the patterns behind their cycles.


Contact info

4.7

Excellent

TrustScore 4.5 out of 5

99 reviews

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Rated 5 out of 5 stars

This company truly cares about women's…

This company truly cares about women's health. Communication has been excellent from pre-purchase to support afterwards as a US customer. I've been using Nettle for 5 months now. Usually I have a sharp transition from ovulation to luteal phase with a drop in mood and onset of physical symptoms with almost 2 weeks of challenging days. While I haven't noticed a dramatic difference, I feel like I now have one to two days back per month and a smoother transition, which is actually a big deal. More importantly, just having another tool in my toolbelt and knowing research is being done on PMS and PMDD feels so good. I almost cried the first time I needed support on a rough day and found a category of luteal phase meditation on the Samphire app. I felt so SEEN.

A few things I wish I knew- as a US customer I needed an adapter for Nettle (but I purchased before the US version as available so that might be why). There is a subscription for the app, and you will need to get refills for sponges every 3 months or so but they are free or affordable if you go through them more quickly. Pro tip- run a session after you've washed your hair, it's much easier to get a strong connection!

30 December 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you for sharing your perspectives and pro tips!! And indeed all Lutea devices come with US chargers :)

Rated 4 out of 5 stars

Soothing stimulation

I have been using Nettle for 4-6 months and I feel very happy with it. I don’t know yet if it’s helping my mood, reactivity, lability, etc., yet! I know that I don’t mind the relaxing and mindful time I get 5 times a month after I shower. I have enjoyed and learned a lot from Emilé’s talks on pms and pmdd. Thank you Nettle and excited to keep trying. The app is good too.

1 July 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience 🫶

Rated 5 out of 5 stars

Nettle

First of all, there is an incredible team behind Nettle — genuinely caring, responsive, and always willing to help. Every question I had was answered with clarity, understanding, and kindness, and the support works at an almost unbelievable speed.

I have been using Nettle for about a year now, and I can truly say it has helped me — a lot — to live a much better quality of life. I have suffered from very painful periods my entire life, and about seven years ago severe PMS symptoms were added to that — intense irritability, emotional overwhelm, and yes, an unstoppable craving for chocolate. I understood that it was PMS, but I had absolutely no tools to work with my emotions.

On top of that, during PMS I was often unable to work for around 7–10 days each month. Then my period itself would last about 5 days, and suddenly I realized that in a 27-day cycle I only had about one “normal” week. This had a huge impact on both my work and overall quality of life.

When I discovered Emilie and learned that she was creating something new, I was one of the very first people to try Nettle. Since then, my PMS has improved dramatically. I no longer feel uncontrollably angry or emotionally overwhelmed, and most importantly — I am functional, productive, and have energy. The menstrual pain that used to be unbearable has significantly decreased. I still take pain medication because the pain is not completely gone, but now it is manageable and the medication works within 15–20 minutes. Before, it often didn’t work at all, leaving me in pain with no options left.

I truly and wholeheartedly recommend this device, because it has genuinely helped me.

I did experience some challenges with the device itself — it sometimes charged very slowly and occasionally wouldn’t charge at all. Eventually, one day it stopped charging completely and appeared to malfunction. However, the support team reacted immediately and wonderfully, and a replacement Nettle is already on its way to me. This level of care and responsibility only strengthens my trust in the brand.

21 December 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience, and we're so glad we were able to smoothly resolve all issues 🫶

Rated 5 out of 5 stars

Nettle is a revolutionary device for…

Nettle is a revolutionary device for taking back the responsabilitues of our health. It s wonderfull to manage ans schedule a session with nettle the moment u need it.
It is very efficient because we can act daily on our pain and discomfort.

9 January 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience!

Rated 5 out of 5 stars

I’ve used nettle for a year now and…

I’ve used nettle for a year now and have noticed a significant difference in my symptoms during my luteal phase. App is easy to use and helpful to track my symptoms !

18 December 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience!! You'll also notice an exciting new feature that brings even deeper insights into your symptoms coming out soon 🫶

Rated 5 out of 5 stars

great addition to PMDD treatment

nettle has been such a great addition to my PMDD treatment, truly not much actually works and especially not without side effects. my nettle (while absolutely not 100% effective), takes the edge off to a more manageable level and is really easy to keep up with as part of my routine. also reduces my cramps a bit which I honestly wasn’t expecting at all! i love that this is a women’s team too, our health is so under-researched, and everyone from samphire has been incredibly responsive when I’ve needed it. looking forward to seeing how this continues to develop!

17 May 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience! Everyone's response is different, but glad you're able to live a bit easier since integrating Nettle into your routine :)

Rated 5 out of 5 stars

A brilliant product and fantastic customer service,

Fantastic customer service, first of all. I had some questions and immediately got answers from Em. It helped so much as I was overwhelmed at first and was scared to do something wrong, but she went through it all with me and I felt so much more confident using it. I have only recently started using the Nettle regularly (after setting up notifications in the app so it reminds me when I need to use it), so I can’t say just yet how much it’s improving my symptoms of PMDD moods and Endometriosis pain, but after being offered the only treatment option of chemically induced menopause by nhs, and declining that, I’m just so happy to have this device as alternative treatment for these very overlooked and underesearched conditions. I’m very hopeful it will help because there are so many positive reviews and Em is very knowledgeable on these conditions. The device is comfortable and easy to use. Once you’ve used it a few times it becomes second nature to go through the steps. It tingles and itches a bit at first but that only lasts a minute for me and then it’s unnoticeable! I can’t wait to see how this device helps me.

15 December 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience - we know too well how heartbreaking it can be to live in pain and yet be offered a single, drastic option. Fingers crossed this is the right solution for you 🫶

Rated 5 out of 5 stars

Nettle is a game changer.

Nettle is a game changer.
I've had it for a year now and it has helped massively with my PMDD. I find it extremely helpful around 10-7 days before my cycle when I feel the most erratic. The feeling when your mind is racing is tuned down almost instantly after using it and I can think in single sentences again.
It helps with endo in reducing the amount of painkillers I take, but I am not really very consistent with it due to my lifestyle/job. I could probably get better results being more consistent.

15 December 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you for sharing your experience! Everyone's cycles and symptoms are different, so it's critical to experiment and find what works best for you 🫶 And hectic lives are part and parcel of everyone's every day, so don't be too hard on yourself and try to stay consistent when you can!

Rated 5 out of 5 stars

Using Nettle has been a life saver!

Using Nettle has been a life saver. I use it on days that my symptoms flare, which for me can also be around ovulation. I can feel relief midway through a session sometimes. It has eased cramps and pain, and mostly been incredible for my mood. It has taken the edge off when I’m really spiraling and has brought me back into a regulated state from a very depressed and overwrought place. I have had less suicidal ideation since using it, and when I did feel it, the Nettle device helped bring my thinking back down into a safe place. I’m very thankful and grateful that it exists.

If you are on the fence (like I was because I was a bit worried about messing with my brain) I would highly recommend trying it because it has improved my life and given me a tool. Before I felt alone in dealing with PMDD, even when consulting professionals. I tried therapy, diet changes, birth control, SSRIs, and supplements. Nettle has done more for me than any of the other interventions I’ve tried and in a faster period of time.

Also Samphire seems like a wonderful company. Their customer service is stellar and responsive. They really care about women’s health and want to improve lives. The app is lovely and I now use that to track everything and am getting better data about my cycle and trends.

14 December 2025
Unprompted review
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Reply from Samphire Neuroscience

🥹🥹🥹 Thank you so much for such a thorough and thoughtful review, and so glad Nettle has been your life saver 🫶

Rated 5 out of 5 stars

Super helpful!

Samphire has been a very supportive company to work with! Any time I've had questions they've responded quickly. And I do think my Nettle does help with my PMDD.

13 December 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you for sharing your experience, and we're always here to support!

Rated 5 out of 5 stars

Nettle changed my life

I use Nettle since January and after a few problems I found my rhythm of using and it helps a lot with my symptoms. I also have adhd and I‘m autistic and I have the feeling, that nettle makes me calmer. The best thing of nettle are the people behind it. The Team is so fantastic and passionate.

12 December 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience! We see so many people with overlapping conditions like yours, and so glad it has been helpful for you so far 🫶

Rated 5 out of 5 stars

Nettle has been such a welcome addition…

Nettle has been such a welcome addition to my PMDD treatment. I love that this has been designed and made by women, for people who are often forgotten by our patriarchal medical systems. Firstly, the team go above and beyond – the care and support is next level, it’s personalised, it’s prompt and I trust the team want the best for me. I do multiple things to manage my PMDD, so it’s hard to pin down the effect of individual treatments, however I can say this has definitely helped raise the floor and level out the extreme drops. Sometimes when I’m having good month and use Nettle anyway, I feel more energised and alert. It’s also a good comfort-blanket to know I have something science-backed and non-invasive whenever I need it. I love that the app gets updated from us, the community. I’ve had a couple of suggestions implemented and that feels wonderful to be part of! No big-pharma or tech-bros over here. Love your work team ❤️

10 March 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for the kind words 🫶 And 100% every person will end up with a different set of solutions - we're all different! And we're here always to help you troubleshoot what works best for you and how neurotechnology can be part of (or the full!) solution for you.

Rated 3 out of 5 stars

My experience wasn't smooth from the…

My experience wasn't smooth from the beginning. I wasn't able to connect Nettle with my personal smartphone. It only worked with other smartphone. And the app itself acts very strange, one time all texts and images/videos are visible, other time no images/videos visible and even text on buttons are not fully visible, it is happening when trying to run session with instruction step by step. Also resently Nettle starts not turning on even it was charged over the night. And I was needed to recharge it again. And next day it is happening again I need to recharge to be able start a session.
I still have hope that it will help me. It is only two cycles of period past, so I can't say if it is really helping. Maybe the mood is better. But still no affection to pain strenght.

11 December 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience! As long as you're using the latest software on your smartphone, this shouldn't be an issue, but we're always happy to troubleshoot with you one-on-one over message or call at support@samphireneuro.com. Most people start seeing best effects around month 3 and onwards, so fingers crossed it keeps getting better and giving you the relief you deserve.

Rated 5 out of 5 stars

Total lifesaver!

I suffer from PMDD and Nettle has been a lifesaver for me! For 2 weeks of every month I used to suffer from extreme anxiety and depression that was debilitating. Since using Nettle my symptoms are so much more manageable. It’s really helped me when I felt I was running out of options. Also, the team that run it are amazing people, they are always there to answer any questions you may have and you can tell they really care! Cannot recommend this product enough!

11 December 2025
Unprompted review
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Reply from Samphire Neuroscience

🥹 thank you for sharing your experience!

Rated 5 out of 5 stars

5***** for PMDD & for women in general

Since joining Samphire and getting the Nettle headband, my life has changed so much. I suffer with PMDD and my periods can vary however since using Nettle, I have seen a significant decrease in physical and mental symptoms and it’s not half as bad as what it’ll my symptoms could be. I’m still quite new to nettle but I honestly won’t ever go without it. Thank you so much to the team at Samphire.

11 December 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank YOU for giving Nettle a try 🫶

Rated 5 out of 5 stars

Life changing

Nettle has completely transformed my life. My PMDD symptoms are significantly reduced and whilst not completely gone, what felt like drowning in a storm now feels like navigating it in a pretty sturdy ship.

I feel like I have more control over my symptoms, I’m able to do more of the things that I do outside of luteal phase, and I have more mental clarity. Instead of my cycle feeling like two opposite ends of the spectrum, it now feels more balanced and less like I have to spend the first week of my cycle recovering from luteal the week before.

Thank you so much Samphire Neuroscience. I discovered Nettle through a Queen Mary University trial and I hope one day for all people who experienced PMDD that it will be available on the NHS. It truly has changed my life

11 December 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you so much for sharing your experience! We are working very hard to have our neurotechnology integrated as part of healthcare pathways, and will continue persevering to make it available on the NHS 💪 In the meantime, we'll continue offering a 3-month returns policy to allow everyone to try Nettle or Lutea risk-free!

Rated 5 out of 5 stars

Excellent Product & Outstanding Customer Care

Samphire is a startup exactly as it should be: delivering an innovative and truly needed product in the way customers actually need it. They stay close, listen carefully to feedback and respond quickly whenever improvements are required.
I’m very satisfied with both the product and the service — highly recommended!

11 December 2025
Unprompted review
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Reply from Samphire Neuroscience

We're working hard every day to bring our best - women should have had it long ago 🙈

Rated 5 out of 5 stars

Absolutely life changing device

Absolutely life changing device. I have seen such a difference in my symptoms since using this. Less pain, fewer mental health concerns. Customer service has been impeccable.

11 December 2025
Unprompted review
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Reply from Samphire Neuroscience

Changing your life is what we're here for!!

Rated 5 out of 5 stars

Life changing for PMDD

I have now been using Nettle for over a year and it is life changing.
PMDD symptoms are vastly reduced.
It is very easy to use, I have very thick hair and it hasn’t been an issue.
Customer service are very responsive and were very helpful when I had charging issues.

11 December 2025
Unprompted review
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Reply from Samphire Neuroscience

Thank you for sharing your experience, especially around how easy it is to use Nettle, Hope! 🫶

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